Nancy A. Shadick, M.D., M.P.H.

nancy-shadick-2008Nancy A. Shadick, M.D., M.P.H.

Dr. Nancy A. Shadick graduated magna cum laude from Barnard College, Columbia University in 1982 and Alpha Omega Alpha from New York University School of Medicine in 1986. She trained in Internal Medicine at the Columbia Presbyterian Medical Center from 1986-1989 and in Rheumatology in our Division from 1989-1992. In 1992 she received a Masters in Public Health in Quantitative Methods from the Harvard School of Public Health. She joined the Brigham & Women’s Hospital staff and Harvard Medical School faculty when her training. In 2010, she was promoted to Associate Professor of Medicine.

Dr Shadick has a national and international reputation for clinical innovation and investigation in Rheumatoid Arthritis (RA) and Lyme disease (LD). As Director of Translational Research Development in the Division of Rheumatology, Dr Shadick founded one of the largest single center cohorts of RA in the nation; the Brigham & Women’s Hospital RA Registry (BRASS). This Registry of over 1300 subjects followed yearly has contributed to expanding our knowledge of integral biomarkers of disease response. 9see teaches in the clinic and her lab and also directs the PACO and PARASS Initiatives for RA patient education. Dr Shadick’s clinical practice consists of referrals with severe RA and Lyme Arthritis. She teaches Rheumatology to students, residents and fellows on the wards and clinic. Her research has received peer reviewed funding by the NIH, CDC, foundation and pharmaceutical grants and she served on many review and professional organization committees.

Dr. Shadick’s clinical innovation relates to 1) the first description, using population-based methodology, of the phenomenon of incomplete recovery from LD leading to a change in treatment recommendations and earlier diagnosis and 2) development of a novel educational program that was the first to result in a reduction in LD cases. In the area of RA, her work has delineated clinical and genetic risk factors for disease severity and inflammatory risk factors for RA incidence. Early in her training she described a novel comorbidity in RA; bronchiectasis. Most recently her clinical innovation is in developing programs that realign care towards the patient perspective on RA patient education and self management initiatives in the R.B. Brigham Arthritis Center

Dr Shadick has provided significant service to the Community in her public health work on Lyme Disease prevention and RA. In LD, with funding from the CDC and the Mass. Dept. of Public Health she has devoted 15 years to educating the public about LD prevention. Her work has been disseminated to over 50,000 residents of the Islands of Martha’s Vineyard, Nantucket and the North Shore of MA. She has given numerous talks to the public about LD recovery and prevention via radio addresses and public service announcements and contributed to local community newsletters, and town meetings. Dr Shadick has also served on the State’s Task Force for Tick-Borne disease control. She developed the first educational program to result in a 40% reduction in LD due to an increase in tick bite precautionary behavior and this novel program became curriculum in the North Shore school system of MA. Dr Shadick consults on LD prevention throughout the state and her work has been incorporated into the Mass Dept of Public Health and CDC sponsored programs that have been disseminated throughout the U.S. (see

As Director of the PACO (Patient Centered Outcomes) and PARASS (Patient RA Social Support) studies, Dr. Shadick has developed educational programs and materials that improve the lives of RA patients. She has designed and organized educational seminars and materials, spearheaded the development of a patient advisory committee, new communication tools (Health Log©) and created the “Living Well with RA©” program a self help intervention that has improved clinical outcomes(see The PARASS study supports a successful peer support program with over 200 peer counseling matches, and a video-journaling program( She has presented nationally at the Annual Scientific Conference about the programs, has written invited reviews, disseminated her educational materials and websites and given many lay presentations to patients about RA treatment from the patient perspective. She maintains an active newsletter available to over 1500 RA patients.

Dr. Shadick’s innovative work on the diagnosis, treatment and prevention of LD and RA has earned her national recognition as an independent clinical expert. As a testament to the respect by her peers for her clinical expertise, Dr. Shadick has been elected “America’s Top Doctors” since 2001 and “Best of Boston” since 2008.